Products

Welcome!
If you are interested in our products，services or solutions, please feel free to consult us through the form below. We will get back to you as soon as possible.

ONLINE INQUIRY

A23187, free acid

Synonyms:

Calcimycin

Cat No.:

LIA048

Price:

Inquiry

Chemical Name:

5-(Methylamino)-2-[[2R,3R,6S,8S,9R,11R)-3,9,11-trimethyl-8-[(1S)-1-methyl-2-oxo-2-(1H-pyrrol-2-yl)-ethyl]-1,7-dioxaspiro[5.5]undec-2-yl]methyl]-4-benzoxazolecarboxylic acid

Chemical Structure：

Description of A23187, free acid

Calcium ionophore

Product Information of A23187, free acid

Purity

≥98% (HPLC)

Molecular Weight

523.63

Formula

C29H37N3O6

CAS Number

52665-69-7

PubChem ID

11957499

Pack Size

10 mg

InChI Key

HIYAVKIYRIFSCZ-CYEMHPAKSA-N

Smiles

[H][C@@]1([C@H](C)C(C5=CC=CN5)=O)[C@H](C)C[C@@H](C)[C@@]2(O[C@H](CC3=NC(C(C(O)=O)=C(NC)C=C4)=C4O3)[C@H](C)CC2)O1

Biological Activity

A23187, free acid is a calcium ionophore that induces Ca²⁺²-dependent cell death by increasing intracellular calcium concentration. Promotes intracelllular ROS generation and platelet particle formation (fragmentation) in vitro and in vivo. Can be used to induce autophagy in mammalian cells.

Storage

Store at 4°C.

For research use only, not intended for any clinical use.