Many exciting discoveries have been made in the field of lysosomal biology, including lysosome biogenesis, integrity maintenance, and physiological functions. As an innovator of lysosomes, CD BioSciences is committed to creating lysosome-based technologies to help your research worry-free. Here, we provide comprehensive lysosome cell biology analysis services. Our professional team will ensure that you get the most satisfactory lysosome service.
Introduction of Lysosomal Cell Biology
Lysosomes are the major proteolytic compartments of mammalian cells and include proteases, nucleases, glycosidases, sulfatase and lipase. In addition, it is involved in nutrient sensing, immune cell signaling, metabolism, and membrane repair. Lysosomal dysfunction not only affects pathways that mediate membrane trafficking that culminates in the lysosome, but also controls metabolic and signaling processes that regulate protein sorting and targeting. Thus, impaired lysosomal function contributes to the pathogenesis of many diseases, including lysosomal storage diseases (LSD), neurodegenerative diseases, and cancer. In recent years, with the development of biotechnology, Chinese cell biologists have made many breakthroughs in lysosomal biology. The biogenesis, integrity maintenance, and physiological functions of lysosomes have attracted extensive research interest.
Fig. 1. Schematic depiction of lysosome-mediated degradation of endocytic, phagocytic and autophagic cargoes, lysosome-peroxisome transport of cholesterol, and lysosomal exocytosis. (Yang C, et al., 2017)
Our services for Lysosomal Cell Biology Analysis
The structural integrity and functional balance of lysosomes are closely related to cell survival and function. Lysosome has become an important research content in cell biology, aiming to reveal the structure, function and life activities of lysosome. With years of experience in lysosome engineering, CD BioSciences provides lysosomal cell biology analysis services to comprehensively evaluate and analyze lysosomal biogenesis processes, etc. Our services focus on the following aspects of lysosomal cell biology:
- Systematic anatomy of lysosomal homeostasis, including biogenesis, dynamics, and maintenance of integrity at the organismal level.
- Dynamic interactions of lysosomes with other intracellular organelles in different cellular processes.
- The role of lysosomes in physiology and pathology.
- Targeting lysosomes to treat lysosome-related diseases, such as LSD and neurodegenerative diseases.
Lysosomal damage can trigger different cell death methods and participate in the occurrence and development of various diseases, such as infections, inflammatory diseases, and tumors. Our goal is to serve you in areas such as lysosomal repair, lysosomal autophagy, and lysosomal regeneration, maintaining cellular homeostasis through quality control of lysosomes. Here, our lysosome structure analysis services include, but are not limited to:
- Glycosylation Analysis of Lysosomal Glycoproteins
- RNAi Screens of Lysosomal Trafficking
- Assessment of Lysosomal-Mediated Plasma Membrane Repair Responses
- Analysis of Lysosomal Membrane Permeability
- Measurement of the Phagocytic Activity of Cells
- Detection and Quantification of Microbial Manipulation of Phagosomal Function
- Analysis of the Function of Lysosomal Calcium in Cell Signaling
- Imaging Measurement of Lysosomal Calcium
Available Advantages
- Supported by a professional team in the field of lysosomes.
- Years of corporate services, rich experience in success.
- High-quality college resources and a wide range of cooperation fields.
- In-depth analysis of needs, accurate matching of colleges and universities.
- The whole process is controlled, and each link is provided with intimate service.
CD BioSciences continues to exploit the potential of lysosomes in an iterative process of insight and innovation. We are committed to providing professional and economical lysosome service projects to global customers. Each project will be custom designed to the client's requirements and described in a detailed project report. We look forward to working with you to discover the charm of lysosomes in our cooperation. If you are interested in our services, please feel free to contact us.
Reference
- Yang C, Wang X. (2017) Cell biology in China: Focusing on the lysosome[J]. Traffic. 18(6): 348-357.