Normal lysosomal function is achieved through the action of two classes of proteins: lysosomal membrane proteins and lysosomal enzymes, mainly soluble lysosomal hydrolases (also known as acid hydrolases). Soluble lysosomal hydrolases constitute the major degrading lysosomal components, and to date, more than 50 hydrolases and their auxiliary proteins have been detected. Lysosomal hydrolases include a variety of peptidases, nucleases, glycosidases, sulfatases, and lipases. Peptidases, a large family of lysosomal hydrolases, are present in all organisms and catalyze the hydrolysis of peptide bonds in different biological processes. Peptides are synthesized by ribosomes and then the peptides enter the endoplasmic reticulum and Golgi apparatus for processing and sorting to form lysosomal peptidases with a certain spatial structure. This is a label that targets lysosomes.
Lysosomal peptidases are hydrolases that digest waste proteins targeted to lysosomes by endocytosis and autophagy. In addition, they play more specific roles in several other cellular processes and pathologies. Lysosomal peptidases are key to the study of lysosomal function. CD BioSciences has advanced peptide synthesis, purification and lyophilization equipment and a complete process to provide one-stop lysosomal peptidase synthesis services. The lysosomal peptidases we are developing include：
❖ Aspartic cathepsins (D and E).
❖ Serine cathepsins (A and G).
❖ Asparagine endopeptidase.
❖ Cysteine cathepsins (B, C, F, H, K, L, O, S, V, W, and X/Z).
Focusing on lysosomal peptide synthesis for many years, CD BioSciences has accumulated rich experience and is able to synthesize peptides of different lengths, different amino acid sequences and different purity levels according to customers' requirements, with guaranteed peptide quality and HPLC and MS test reports. Our goal is to provide you with high quality lysosomal peptidases. We have a proven track record of supporting partners in various fields and can provide you with tailored solutions for your lysosomal peptidase applications. Our portfolio of life science research products allows you to leverage our extensive experience.
We have provided custom lysosomal peptidase services to over 1000+ customers, covering research institutions and some biological companies in many countries around the world, and have been well received.
Applications of Lysosomal Peptidases
CD BioSciences continues to expand and update its extensive line of lysosomal peptidases for lysosomal scientific research, such as:
- Analysis of the role of lysosomal peptidases in specific pathological processes of cancer and neurodegeneration.
- Regulation of lysosomal activity and stability of lysosomal glycosidases.
- Analysis of the role of lysosomal peptidases in antigen and autoantigen processing.
- Acting as an early biomarker for certain types of cancer.
- Regulating the activity of a variety of peptides, growth factors and enzymes and the degradation of misfolded, long-lived and denatured proteins.
Why Choose Us?
- Customer focus and service—We offer the highest quality products and services in the industry, and we represent a trusted long-term partnership. Our customers appreciate our extensive knowledge, experience and expertise in the entire field of peptide development and production.
- Innovation and technology—We are passionate about innovation and focused on delivering value in all areas of our company.
- Operational excellence and quality—The pharmaceutical and biotechnology business requires the most rigorous manufacturing standards in the world and demands absolute perfection in quality.
- People and culture—Our people make a difference. We are passionate about technology and continuous innovation, while taking pride in our reliability and solution-oriented practices.
CD BioSciences offers a wide range of professional lysosomal peptidases. Our aim is to provide the latest, economical and rapid lysosomal peptidases to customers around the world. Over the years, we have continuously expanded our products to meet the needs of lysosomal science research. If you are interested in our products, please contact us for product quotation and more detailed information.