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EACC

Cat No.:

LIA009

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Chemical Structure：

Description of EACC

EACC selectively inhibits the translocation of autophagosome-specific SNARE Stx17 thereby blocking autophagosome-lysosome fusion.

Product Information of EACC

Purity

0.9925

Molecular Weight

369.37

Formula

C₁₃H₁₁N₃O₆S₂

CAS Number

864941-31-1

Pack Size

Free Sample (0.1-0.5 mg)
10 mM * 1 mL in DMSO
5 mg/10 mg/50 mg/100 mg/200 mg/500 mg

Target

Autophagy

Applications

EACC is a reversible autophagy inhibitor, which can block autophagic flux.

Shelf-Life

Powder：
-20°C, 3 years.
4°C, 2 years.

In solvent:
-80°C, 6 months.
-20°C, 1 month.

Shipping Conditions

Room temperature in continental US, may vary elsewhere.

In Vitro Studies

EACC blocks autophagosome-lysosome fusion but does not affect endo-lysosomal function.
EACC inhibits autophagy by preventing SNARE Stx17 loading on autophagosomes.
EACC does not affect RABs, tethers, and lysosomal SNARE but prevents their interaction with LC3 and Stx17.

For research use only, not intended for any clinical use.