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Galangin

Cat No.:

LIA060

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Chemical Name:

3,5,7-Trihydroxy-2-phenyl-4H-1-benzopyran-4-one

Chemical Structure：

Description of Galangin

TRPC5 inhibitor; also induces autophagy

Product Information of Galangin

Purity

≥98% (HPLC)

Molecular Weight

270.24

Formula

C15H10O5

CAS Number

548-83-4

PubChem ID

5281616

Pack Size

25 mg

InChI Key

VCCRNZQBSJXYJD-UHFFFAOYSA-N

Smiles

OC1=CC(O)=C2C(OC(C3=CC=CC=C3)=C(C2=O)O)=C1

Biological Activity

Galangin is a TRPC5 inhibitor. Inhibits Ca²⁺² entry into TRPC5 expressing cells. Inhibits LPS-induced expression of TNFα, IL-6, IL-1β, COX2 and iNOS, in vitro. Attenuates microglial activation, loss of dopaminergic neurons and motor dysfunction in a LPS-induced rat model of ParkinsoN^'s disease. Also inhibits proliferation in breast cancer cell lines. Induces autophagy. Also displays antiviral activity against HSV-1, coxsackie B virus type 1, adenovirus type 31 and reovirus.

Storage

Store at -20°C.

For research use only, not intended for any clinical use.