Products

Welcome!
If you are interested in our products，services or solutions, please feel free to consult us through the form below. We will get back to you as soon as possible.

ONLINE INQUIRY

Indo 1AM

Cat No.:

LSK008

Price:

Inquiry

Chemical Name:

2-[4-[Bis[2-[(acetoxy)methoxy]-2-oxoethyl]amino]-3-[2-[2-[bis[2-[(acetyloxy)methoxy]-2-oxoethyl]amino]-5-methylphenoxy]ethoxy]phenyl]-1H-indole-6-carboxylic acid (acetoxy)methyl ester

Chemical Structure：

Description of Indo 1AM

Fluorescent Ca²⁺ indicator

Product Information of Indo 1AM

Purity

≥90% (HPLC)

Molecular Weight

1009.91

Formula

C47H51N3O22

CAS Number

112926-02-0

PubChem ID

123918

Pack Size

1 mg

InChI Key

CAWBRCOBJNWRLK-UHFFFAOYSA-N

Smiles

CC(=O)OCOC(=O)CN(CC(=O)OCOC(C)=O)C1=C(OCCOC2=C(C=CC(=C2)C2=CC3=C(N2)C=C(C=C3)C(=O)OCOC(C)=O)N(CC(=O)OCOC(C)=O)CC(=O)OCOC(C)=O)C=C(C)C=C1

Biological Activity

Indo 1AM is a fluorescent Ca²⁺ indicator (Kd for Ca²⁺ = 250 nM). Cell-permeable. Displays ratiometric emission wavelength change upon Ca²⁺ binding. Excitation/emission λ are 355/475 nm for no Ca²⁺ and 355/401 nm for high Ca²⁺. Absorption maxima are 349 and 331 nm for free anion and Ca complex, respectively. Respective emission maxima are 485 and 410 nm. Quantum yield ~0.5. Ideal for flow cytometry.

Storage

Store at -20°C.

For research use only, not intended for any clinical use.