Products

Welcome!
If you are interested in our products，services or solutions, please feel free to consult us through the form below. We will get back to you as soon as possible.

ONLINE INQUIRY

Indomethacin-d4 Methyl Ester

Cat No.:

LIL002

Price:

Inquiry

Chemical Structure：

Description of Indomethacin-d4 Methyl Ester

Indomethacin-d4 Methyl Ester is the deuterium labeled Indomethacin. Indomethacin (Indometacin) is a potent, blood-brain permeable and nonselective inhibitor of COX1 and COX2. Indomethacin disrupts autophagic flux by disturbing the normal functioning of lysosomes.

Product Information of Indomethacin-d4 Methyl Ester

Molecular Weight

375.84

Formula

C₂₀H₁₄D₄ClNO₄

CAS Number

1217064-61-3

Pack Size

1 mg/10 mg

IC₅₀

Human COX-1: 18 nM in CHO cells
Human COX-2: 26 nM in CHO cells

Target

Human COX-1
Human COX-2

Storage

Store at -20°C, protect from light

Shipping Conditions

Room temperature in continental US, may vary elsewhere.

In Vitro Studies

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.

For research use only, not intended for any clinical use.