Products

Welcome!
If you are interested in our products，services or solutions, please feel free to consult us through the form below. We will get back to you as soon as possible.

ONLINE INQUIRY

LCL521

Cat No.:

LIA008

Price:

Inquiry

Chemical Structure：

Product Information of LCL521

Molecular Weight

592.77

Formula

C₃₁H₅₂N₄O₇

CAS Number

1226851-11-1

Pack Size

10 mM * 1 mL in DMSO
5 mg/10 mg/50 mg/100 mg

Target

ACDase, ASMase.

Applications

LCL521 is an acid ceramidase (ACDase) inhibitor. LCL521 also inhibits the lysosomal acid sphingomyelinase (ASMase).

Shelf-Life

Pure form:
-20°C 3, years.

In solvent:
-80°C, 6 months.
-20°C, 1 month.

Shipping Conditions

Room temperature in continental US, may vary elsewhere.

In Vitro Studies

LCL521 (1 µM) acts as a potent inhibitor of cellular ACDase activity, whereas 10 µM LCL521 has an additional, decreased affect on the α-form of this enzyme. LCL521 (10 µM) causes a time-dependent (1 hours and 5 hours) decrease of the α-ACDase form in MCF7 cells.

For research use only, not intended for any clinical use.