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Metformin hydrochloride

Cat No.:

LIA063

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Chemical Name:

N,N-Dimethylimidodicarbonimidic diamide hydrochloride

Chemical Structure：

Description of Metformin hydrochloride

Activator of LKB1/AMPK; antidiabetic agent

Product Information of Metformin hydrochloride

Molecular Weight

165.62

Formula

C4H11N5.HCl

CAS Number

1115-70-4

PubChem ID

14219

Pack Size

100 mg

InChI Key

OETHQSJEHLVLGH-UHFFFAOYSA-N

Smiles

NC(NC(N(C)C)=N)=N.Cl

Biological Activity

Metformin hydrochloride is an antidiabetic agent; lowers plasma glucose levels and improves insulin sensitivity. Inhibits hepatic gluconeogenesis via activation of the LKB1/AMPK pathway. Displays antiproliferative effects in cancer cell lines via inhibition of mitochondrial complex I (MRC-1). Activates the aPKC-CBP pathway in neural precursors to promote neurogenesis. Activates autophagy. Identified by chemoinformatics as targeting human host proteins that interact with SARS-CoV-2.

Storage

Store at room temperature.

For research use only, not intended for any clinical use.