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OG 488 BAPTA-1 AM

Cat No.:

LSK011

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Chemical Name:

N-[2-[(Acetyloxy)methoxy]-2-oxoethyl]-N-[4-[[[3^',6'-bis(acetyloxy)-2',7'-difluoro-3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthen]-5-yl]carbonyl]amino]-2-[2-[2-[bis[2-[(acetyloxy)methoxy]-2-oxoethyl]amino]phenoxy]ethoxy]phenyl]glycine (acetyloxy)methyl ester

Chemical Structure：

Description of OG 488 BAPTA-1 AM

Cell-permeable, fluorescent Ca²⁺ indicator

Product Information of OG 488 BAPTA-1 AM

Purity

≥90% (HPLC)

Molecular Weight

1258.06

Formula

C59H53F2N3O26

CAS Number

244167-57-5

PubChem ID

102028682

Pack Size

1 mg

InChI Key

NQVWLDWXFNDFLA-UHFFFAOYSA-N

Smiles

FC1=CC2=C(C3=CC=C(C(NC4=CC=C(N(CC(OCOC(C)=O)=O)CC(OCOC(C)=O)=O)C(OCCOC5=CC=CC=C5N(CC(OCOC(C)=O)=O)CC(OCOC(C)=O)=O)=C4)=O)C=C3C([O-])=O)C6=CC(F)=C(OC(C)=O)C=C6[O+]=C2C=C1OC(C)=O

Biological Activity

OG 488 BAPTA-1 AM is a cell-permeable, fluorescently labeled Ca²⁺ indicator. Composed of a green fluorescent probe (OG 488, Cat. No. 6257) conjugated to a cell-permeable Ca²⁺ chelator (BAPTA AM, Cat. No. 2787). Fluorescent intensity increases approximately 14-fold from resting intensity, upon Ca²⁺ binding. Displays uniform cellular distribution with minimal subcellular compartmentalization. Excitation/emission λ 494/523 nm.

Storage

Store at -20°C.

For research use only, not intended for any clinical use.