Products

Welcome!
If you are interested in our products，services or solutions, please feel free to consult us through the form below. We will get back to you as soon as possible.

ONLINE INQUIRY

Taxol

Synonyms:

Paclitaxel

Cat No.:

LIA043

Price:

Inquiry

Chemical Name:

[2aR-[2aα,4β,4aβ,6α,9α(αR*,βS*),11α,12α,12aα,12bα]]-β-(Benzoylamino)-α-hydroxy-6,12b-bis(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12,12b-dodecahydro-4,11-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl ester benzenepropanoic acid

Chemical Structure：

Description of Taxol

Promotes assembly and inhibits disassembly of microtubules

Product Information of Taxol

Purity

≥98% (HPLC)

Molecular Weight

853.92

Formula

C47H51NO14

CAS Number

33069-62-4

PubChem ID

441276

Pack Size

10 mg/50 mg

InChI Key

RCINICONZNJXQF-VAZQATRQSA-N

Smiles

O=C2[C@@]3(C)C([C@@]4(OC(C)=O)[C@H](OC4)C[C@@H]3O)[C@H](OC(C7=CC=CC=C7)=O)[C@@]1(O)[C@](C)(C)C([C@H]2OC(C)=O)=C(C)[C@@H](OC([C@H](O)[C@H]([C@]5=CC=CC=C5)NC(C6=CC=CC=C6)=O)=O)C1

Biological Activity

Taxol, also known as paclitaxel, promotes and stabilizes tubulin polymerization, causing cell cycle arrest. In CCRF-HSB-2 cells, Taxol induces autocatalytic activation of caspase-10, triggering apoptosis. Taxol is an antitumor agent. In a mouse model of bladder cancer Taxol decreases tumor growth. Taxol also prolongs survival of mice transplanted with human ovarian carcinoma xenografts. Taxol improves neurological outcome and magnetic resonance imaging biomarkers after traumatic brain injury in mice.

Storage

Store at 4°C.

For research use only, not intended for any clinical use.